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Melanomas appear Because of the mixture of numerous Determining factors. Nonetheless, this is not the only thing. There is a variable as powerful as genetics itself, and that's solar exposure.



How can The problem start?
• Melanocytes (the cells responsible for forming melanin( and melanomas) become far more active when stimulated by these photons. It follows that when exposed to the sun, the melanocytes have greater cellular action, and so, skin tone darkens because of the production of excess melanin.
• This is made as a protective response. While bigger melanocytes are in the epidermis, the greater the barrier pose to those UV rays that could influence the entire body. But this constant subungual melanoma exposure can affecteventuallythe operation of these cells. Their destruction or excessive action can generate considerable consequences, and one of them is their abnormal reproduction.
• This is a result of the high ability of renewal of these epithelial cells of their very superficial layer of the skin. The destruction of this melanocyte can affect it at the genetic level, within the bases which compose its DNA, and generate that inappropriate orders are generated that direct the cells to uncontrolled reproduction.



In the Event of a nodular Melanoma, these cells carry out this process much more rapidly. This is only one of the most delicate cases that can be treated, and usually they are inherent in lifestyle, but at a high percent they are a consequence of the described problem.
The reverse occurs in a subungual melanoma, in which the causes of appearance are usually others. In Reality, they appear in one one of reduced exposure to the sun (under The claws ) and in people of dark complexion, which provides clear indications of Other origins.